Florida police and the FBI were searching for the boyfriend of missing Florida woman, Gabby Petito, on Friday after his family said they had not seen him in three days.

The disappearance of Brian Laundrie, 23, may further complicate the search for Gabby Petito, who was reported missing on Sept. 11.

The couple had left on a cross-country road trip in June. Laundrie returned home alone to North Port, Fla.

“The family called us there this evening. They are now claiming they have not seen their son since Tuesday," North Port Police spokesman Josh Taylor told CNN.

A Florida attorney representing Laundrie told local broadcaster WSPA-TV that his whereabouts were unknown and that police and FBI agents were looking for him.

Laundrie, who lived with Petito, 22, in North Port, which is 70 miles south (approximately 112 kilometres) of St. Petersburg on Florida's west coast, has refused to speak with investigators.

Police have labelled him a "person of interest" not a suspect, in the high-profile disappearance, which has made headlines even as police say they have no solid evidence that a crime has been committed.

Laundrie's attorney has defended his client's silence, saying that anything he told police could be used against him later, "regardless of whether my client had anything to do with Ms. Petito's disappearance."

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